The purpose of this study is to determine if the study drug, inhaled nitric oxide (iNO), when given and breathed through an investigational study device, the INOpulse, may help treat patients at risk for pulmonary hypertension-pulmonary fibrosis. Another purpose of this study is to determine if using the INOpulse delivery device (drug and device combination) improves the levels of moderate to vigorous physical activity (for example walking, climbing stairs, household chores and cleaning and, exercise and hobbies), as measured by actigraphy (a non-invasive way to monitor rest/activity).
The purpose of the study is to demonstrate the safety and effectiveness of the BioVentrix Revivent TC System for the treatment of LV antero-septal aneurysms/scars in patients with symptomatic heart failure.
NXDC-MEN-301: Subjects are being asked to participate in this study because they have a brain tumor, a meningioma, and surgery is recommended to remove it. The sponsor of this clinical trial, NX Development Corp, has developed the study drug, Gleolan, an imaging agent that in some brain tumors, can make the tumors glow red-violet under a special blue light. This may make it easier for the study surgeon to identify the tumor and to remove it. As part of the study, subjects will drink the Gleolan before your surgery. The goal is to safely remove the tumor.