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clinical trials

Clinical trials and research studies

At SIU Medicine, our researchers perform clinical trials and research studies with the aim of translating findings into new, more effective treatments.
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Activity Status

  • Active, not recruiting (2)
  • Active, recruiting (2)

Treatment

  • Alzheimer's Disease (3)
  • Congestive Heart Failure (1)
  • Dementia (1)

Department

  • (-) Alzheimer's Center (3)
  • (-) Cardiothoracic Surgery (1)
  • Internal Medicine (1)
  • Neurology (7)
  • Neuroscience Institute (1)
  • Neurosurgery (1)
  • Psychiatry (1)
  • Pulmonary and Critical Care (1)
  • Surgery (1)
Reset

Filter Results

Activity Status

  • Active, not recruiting (2)
  • Active, recruiting (2)

Treatment

  • Alzheimer's Disease (3)
  • Congestive Heart Failure (1)
  • Dementia (1)

Department

  • (-) Alzheimer's Center (3)
  • (-) Cardiothoracic Surgery (1)
  • Internal Medicine (1)
  • Neurology (7)
  • Neuroscience Institute (1)
  • Neurosurgery (1)
  • Psychiatry (1)
  • Pulmonary and Critical Care (1)
  • Surgery (1)
Showing: 4 Results
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Trial
Neurology

Athira: A Randomized, Placebo-Controlled, Double-Blind, Dose-Ranging Study to Evaluate Safety and Efficacy of ATH-1017 Treatment in Alzheimer’s Dementia Patients

Active recruiting

ATH-1017-AD-201: The purpose of this study is to compare the effects, good or bad, of ATH-1017 on patients with mild to moderate Alzheimer's Disease.

Contact: Sara Boarman phone217-545-6829 emailsboarman93@siumed.edu
Trial
Cardiothoracic Surgery

Clinical Study of the BioVentrix TC System for the Treatment of Left Ventricular Aneurysm

Active recruiting

The purpose of the study is to demonstrate the safety and effectiveness of the BioVentrix Revivent TC System for the treatment of LV antero-septal aneurysms/scars in patients with symptomatic heart failure.

Contact: Katie Mottershaw phone217-545-7387 emailkmottershaw33@siumed.edu
Trial
Neurology

Lilly: Assessment of Safety, Tolerability, and Efficacy of Donanemab in Early Symptomatic Alzheimer's Disease

Active not recruiting

I5T-MC-AACI: Alzheimer’s is a disease that attacks the brain, causing problems with memory, thinking, and behavior.  Symptoms usually develop slowly and get worse over time, eventually making daily tasks impossible. Although we don’t know the exact cause, researchers found out that the two proteins called tau and amyloid are building up in brains of people with Alzheimer’s disease even before they have any symptoms.

Contact: Barbara Lokaitis phone217-545-9737 emailblokaitis@siumed.edu
Trial
Neurology

Roche: A Phase II, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Efficacy and Safety Study of MTAU9937A in Patients with Moderate Alzheimer's Disease

Active not recruiting

Lauriet: The purpose of this study is to compare the effects, good or bad, of MTAU9937A versus placebo on patients with moderate AD.  In this study, you will get either MTAU9937A or placebo.  MTAU9937A is an experimental drug, which means health authorities such as the Food and Drug Administration (FDA) have not approved it for the treatment of moderate AD or other conditions.  MTAU9937A is in early development and has been previously studied in healthy subjects and people with milder forms of Alzheimer’s disease.

Contact: Stephanie Kohlrus phone217-545-3013 emailskohlrus@siumed.edu
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