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clinical trials

Clinical trials and research studies

At SIU Medicine, our researchers perform clinical trials and research studies with the aim of translating findings into new, more effective treatments.
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Activity Status

  • Active, not recruiting (1)
  • Active, recruiting (6)

Treatment

  • (-) High Blood Pressure (Hypertension) (4)
  • (-) Parkinson's Disease (3)
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  • Transcranial Magnetic Stimulation (TMS) (1)

Department

  • Internal Medicine (1)
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Reset

Filter Results

Activity Status

  • Active, not recruiting (1)
  • Active, recruiting (6)

Treatment

  • (-) High Blood Pressure (Hypertension) (4)
  • (-) Parkinson's Disease (3)
  • Abdominal Aortic Aneurysm (1)
  • Alzheimer's Disease (5)
  • Congestive Heart Failure (1)
  • Dementia (1)
  • Depression (1)
  • Diabetes (1)
  • Endometrial Cancer (1)
  • Endometriosis (1)
  • Heart Disease (1)
  • Male Infertility and Sexual Dysfunction (1)
  • Muscular Dystrophy (1)
  • Ovarian Cancer (1)
  • Psoriasis (1)
  • Stroke (1)
  • Transcranial Magnetic Stimulation (TMS) (1)

Department

  • Internal Medicine (1)
  • Neurology (2)
  • Pulmonary and Critical Care (1)
Showing: 7 Results
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Trial
Pulmonary and Critical Care

A randomized, double-blind, placebo-controlled dose escalation and verification clinical study to assess the safety and efficacy of pulsed, inhaled nitric oxide in subjects at risk of pulmonary hypertension associated with pulmonary fibrosis on long term oxygen therapy

Active recruiting
The purpose of this study is to determine if the study drug, inhaled nitric oxide (iNO), when given and breathed through an investigational study device, the INOpulse, may help treat patients at risk for pulmonary hypertension-pulmonary fibrosis. Another purpose of this study is to determine if using the INOpulse delivery device (drug and device combination) improves the levels of moderate to vigorous physical activity (for example walking, climbing stairs, household chores and cleaning and, exercise and hobbies), as measured by actigraphy (a non-invasive way to monitor rest/activity).
Contact: Rebecca Coughlin phone217-545-7321 emailrcoughlin59@siumed.edu
Trial
Neurology

AbbVie: A prospective observational study to evaluate the clinical outcomes and burden of disease of PD patients with motor fluctuations not adequately controlled by current PD medications.

Active not recruiting

PROSPECT:  This is an observational study and is designed to describe the clinical outcomes and the burden of disease in PD patients with motor fluctuations not adequately controlled by current PD medications.

Contact: Sara Boarman phone217-545-6829 emailsboarman93@siumed.edu
Trial
Neurology

Phase 2b/3, Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter Study to Evaluate the Safety and Efficacy of Dipraglurant (ADX48621) for the Treatment of Dyskinesia in Patients with Parkinson's Disease Receiving Levodopa-based Therapy With or Without Concomitant Dopaminergic Medications

Active recruiting

The purpose of this study is to evaluate the effectiveness, safety, and tolerability of the investigational drug, dipraglurant (ADX48621), in subjects with Parkinson’s disease (PD) and levodopa-induced dyskinesia (LID).

 

Contact: Sara Boarman phone217-545-6829 emailSara Boarman
Trial
Internal Medicine

RADIANCE Continued Access Protocol (CAP): A study of the ReCor Medical Paradise System in Clinical Hypertension

Active recruiting

PURPOSE: This purpose of this clinical trial is to find out if a medical device called the Paradise Renal Denervation System
can lower blood pressure in patients who have hypertension

Contact: Emily Starkey phone217-545-7616 emailestarkey74@siumed.edu
Trial
Internal Medicine

REFRESH: A Phase 3, Double-blind, Placebo-controlled and Open-label Efficacy and Long-term Safety Study of Firibastat (QGC001) Administered Orally, Once Daily, for Up to 48 Weeks in Patients with Difficult-to-treat/Resistant Hypertension

Active recruiting

PURPOSE: The purpose of this clinical trial is to assess the effects of firibastat on blood pressure, in patients with difficult-to-treat and/or treatment-resistant hypertension

Contact: Emily Starkey phone217-545-7616 emailestarkey74@siumed.edu
Trial
Neurology

Roche: A Phase IIB, randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety of intravenous prasinezumab in participants with early Parkinson's disease

Active recruiting

PADOVA: The purpose of this study is to find out what effects, good and/or bad, prasinezumab versus placebo has on Parkinson’s disease in people who are taking standard medication to manage the disease symptoms.

Contact: Sara Boarman phone217-545-6829 emailsboarman93@siumed.edu
Trial
Internal Medicine

The "RADIANCE II" Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension

Active recruiting
The purpose of this clinical study is to see whether a medical device called the Paradise Renal Denervation System (also called The Paradise System) can lower high blood pressure in patients who are known to have hypertension.
Contact: Emily Starkey phone217-545-7616 emailestarkey74@siumed.edu
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